The human 8-oxoguanine DNA glycosylase OGG1 is involved in base excision repair (BER). one of several DNA repair mechanisms that may counteract the effects of chemo- and radiation therapy for the treatment of cancer. We envisage that potent inhibitors of OGG1 may be found among the 9-alkyl-8-oxoguanines. Thus we explored synthetic routes to 8-oxoguanines and examined these as OGG1 inh... https://powerhousefilmers.shop/product-category/limited-editions/